Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNJ8 All Species: 24.85
Human Site: S354 Identified Species: 60.74
UniProt: Q15842 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15842 NP_004973.1 424 47968 S354 K V A A P R C S A R E L D E K
Chimpanzee Pan troglodytes XP_521849 390 43540 E321 R F V P I V A E E D G R Y S V
Rhesus Macaque Macaca mulatta XP_001098781 424 47979 S354 K V A A P R C S A R E L D E K
Dog Lupus familis XP_543766 424 47935 S354 K V A A P R C S A R E L D E K
Cat Felis silvestris
Mouse Mus musculus P97794 424 47961 S354 R V A A P R C S A R E L D E K
Rat Rattus norvegicus Q63664 424 47944 S354 R V A A P R C S A R E L D E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519724 340 37133 I270 D E K P S I L I Q A L Q R S E
Chicken Gallus gallus Q90854 492 55398 S349 E V P T P P Y S V K E Q E E M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001025324 416 46812 S346 K V A T P R C S A R E L D E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52192 505 57401 A388 T Y P V R T P A M S P A E F Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.8 99.7 99.7 N.A. 98.3 97.6 N.A. 67.4 38.8 N.A. 78.5 N.A. N.A. N.A. 32.4 N.A.
Protein Similarity: 100 79.9 99.7 100 N.A. 98.5 98.1 N.A. 72.8 58.5 N.A. 87 N.A. N.A. N.A. 50.8 N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 0 33.3 N.A. 93.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 53.3 N.A. 93.3 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 60 50 0 0 10 10 60 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 10 0 0 60 0 0 % D
% Glu: 10 10 0 0 0 0 0 10 10 0 70 0 20 70 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 40 0 10 0 0 0 0 0 0 10 0 0 0 0 60 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 10 60 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 20 20 70 10 10 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 20 0 0 0 % Q
% Arg: 30 0 0 0 10 60 0 0 0 60 0 10 10 0 0 % R
% Ser: 0 0 0 0 10 0 0 70 0 10 0 0 0 20 0 % S
% Thr: 10 0 0 20 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 70 10 10 0 10 0 0 10 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _